Space using ratios
Hot Tip #28 is to space using ratios.
For example, set a base size of 8px, then define your padding using multiples of 8:
Tiny gaps = 8px
Small gaps = 16px
Medium gaps = 32px
Big gaps = 64px

Using ratios aligns your content better and tightens up Landing Page design.
- 8-Point Grid System – Very good visual breakdown by Elliot Dahl of the benefits an 8pt system give a design. Includes 8px ratio infographics.